Godinho colloquia will discuss how improving the performance of the column remains paramount to the continued growth of ultrahigh pressure liquid chromatography. Realization of the theoretical benefits associated with sub-2 μm chromatographic supports requires homogenous packing of the sorbent into a column. This is challenging as dispersion due to transcolumn heterogeneities become increasingly important as packing material continues towards smaller particles. There are many studies on slurry packing, the process is highly dynamic and influenced by many interdependent parameters and the results of these studies have yielded many opinions on the art of column packing as opposed to the science.
Wall Academic Center WALL-320 Classroom
Yates, Alexis C