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Course DescriptionA continuation of the study of calculus and other mathematical methods for modeling change. Topics include multivariable calculus, and systems of linear equations, difference equations and differential equations. The last three weeks of the course is devoted to the study of uncertainty, using probability models such as Bayes' rule and random walks. Students will be guided in the discovery and mastery of mathematical techniques in the context of problems in the life sciences. |
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Bio-Math Connections Fridays 4-5 p.m.
Date |
Topic |
Reading |
Homework Assignment |
Jan 14 |
Functions of Several Variables |
GRL 9.1 |
GRL Section 9.1 (p. 484) |
Jan 16 |
Partial Derivatives |
GRL 9.2 |
GRL Section 9.2 (p. 495) |
Jan 18 |
Maxima and Minima |
GRL 9.3 |
GRL Section 9.3 (p. 507) #22, 24, 26, 32 Solutions |
Jan 21 |
HOLIDAY |
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Jan 23 |
Chain Rule for Partial Derivatives |
Problems | |
Jan 25 |
Multiple Integration |
GRL 9.5 |
Solutions |
Jan 28 |
Multiple Integration, cont. |
GRL 9.5 |
Solutions |
Jan 30 |
Multivariable Calculus Models & Recap |
Extra double integral problems and solutions | |
Feb 1 |
Review I |
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Feb 4 |
Systems of Equations |
GRL 10.1 |
GRL Section 10.1 #26, 32, 40, 43, 48, and balance three chemical equations sent by email. Solutions |
Feb 6 |
Structured Population Models |
AR 2.1 |
AR Section 2.1 (p. 52) #2.1.6 |
Feb 8 |
Matrix Algebra and Excel |
GRL 10.2-10.3 |
Solutions |
Feb 11 |
Leslie Matrices |
AR 2.2 |
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Feb 13 |
Small world networks (PIN1; PIN2; 6 degrees; Kevin Bacon) |
GRL 10.4 |
Solutions |
Feb 15 |
Eigenvalues and Eigenvectors TED |
AR 2.3 |
Solutions |
Feb 18 |
Eigenvalues and Eigenvectors (Geometric interpretation) |
GRL 10.5 |
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Feb 20 |
More Linear Algebra Models & Recap |
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Feb 22 |
Review II |
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Feb 25 |
Fitting Curves to Data (IDH data) |
AR 8.1 |
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Feb 27 |
Least Squares (Linear Models) |
GRL 1.2 |
IDH Excel validation GRL Section 1.2 (p. 27) #7,9 GRL Section 10.1 (p. 549) #52 |
Feb 29 |
Least Squares, cont. (Exponential curve-fitting) |
AR 8.3 |
Two problems in Excel file |
Mar 3-7 |
SPRING BREAK |
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Mar 10 |
Predator-Prey Models
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AR 3.1 |
AR Section 3.1 #3, 5 |
Mar 12 |
Equilibria |
AR 3.2 |
N/A |
Mar 14 |
Stability |
AR 3.3 |
AR Section 3.2 #1, 3; Section 3.3 #7 |
Mar 17 |
Competition, Mutualism, and Infection |
AR 3.4 |
AR Section 3.4 #3-5 |
Mar 19 |
Recap interacting population models |
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Project #1 assigned |
Mar 21 |
Project work day - no class |
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Mar 24 |
HOLIDAY |
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Mar 26 |
Simple Epidemic Models |
AR 7.1 |
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Mar 28 |
TBA | Project #1 due at 5:00 p.m. via email | |
Mar 31 |
Thresholds and Critical Parameters | AR 7.2 | |
Apr 2 |
Other Infectious Disease Models |
AR 7.3 |
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Apr 4 |
Review III |
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Apr 7 |
Event Trees and Sets |
GRL 12.1 |
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Apr 9 |
Basic Probability Rules |
GRL 12.2 |
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Apr 11 |
Random Walks in Biology |
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Apr 14 |
Basic Probability Rules , cont. | GRL 12.2 | |
Apr 16 |
Conditional probability and independent events |
GRL 12.3 |
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Apr 18 |
Bayes Rule |
GRL 12.3 |
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Apr 21 |
Discrete Random Variables |
GRL 12.4 |
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Apr 23 |
Genetics and the Binomial Distribution |
AR 6.1-6.2 |
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Apr 25 |
Probability Models & Recap |
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Apr 28 |
Review IV |
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Apr 30 |
Case Study (CAT scans) |
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May 2 |
Final exam preparation |
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May 5 |
Project presentations |
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May 7 |
Project presentations & Course evaluations |
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May 9-14 |
Final Exam period |
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